Neuroma

• Tumor of neural tissue; two types which include traumatic neuroma (amputation neuroma) and palisaded encapsulated neuroma (PEN)
• Often presents as solitary skin-colored to erythematous firm papule, ± associated pain (occurs as site of trauma if traumatic neuroma)
• Histology:
  • Traumatic neuroma: well-circumscribed nodule consisting of fascicles of peripheral nerve arranged in a haphazard pattern
  • PEN: well-demarcated proliferation of palisading spindle cells with encapsulation and fibrotic stroma