| | | | | | | | | | | | | Three to five percent of the population have an allergy to bovine collagen | | | | | | | | |
|
| | | | | | | | | | |
| Table 6-22 Injectable Fillers |
| | Name | | Composition | | Duration
(months) | | Level of implantation | | Comments |
| | Cosmoderm I | | Human collagen + plain lidocaine | | 3–4 months | | Superficial to mid-dermis | | No pretesting, from neonatal foreskin |
| | Zyderm I | | Bovine collagen + lidocaine | | 3–4 months | | Superficial to mid-dermis | | + Pretesting (two tests 2–4 weeks apart) |
| | Autologen | | Human collagen
(from pt’s own skin) | | 4–9 months | | Mid-dermis | | No pretesting |
| | Hylaform | | Hyaluronic acid (from rooster comb) | | 3–6 months | | Mid-dermis | | No pretesting |
| | Restylane | | Hyaluronic acid (from bacterial fermentation) | | 4–6 months | | Mid-dermis | | No pretesting |
| | Zyderm II | | Bovine collagen + plain lidocaine | | 3–6 months | | Mid-dermis | | + Pretesting |
| | Artecoll | | Polymethylmethacrylate beads in bovine collagen suspension | | Permanent | | Deep dermis | | + Pretesting |
| | Cosmoplast | | Human collagen crosslinked w/ glutaraldehyde + plain lidocaine | | 3–4 | | Deep dermis | | |
| | Hyaloform plus | | Hyaluronic acid
(rooster comb) | | 3–6 | | Deep dermis | | |
| | Perlane | | Hyaluronic acid (bacterial fermentation) | | 3–9 | | Deep dermis | | |
| | Zyplast | | Bovine collagen crosslinked w/ glutaraldehyde + plain lidocaine | | 3–5 | | Deep dermis | | + Pretesting |
| | Isolagen | | Cultured autologous human fibroblasts | | Unclear | | Versatile | | |
| | Juvederm | | Hyaluronic acid | | 3–6 | | Dermis (level varies if ultra or plus) | | |
| | Radiesse | | Calcium hydroxylapatite microspheres in polysaccharide gel | | 9 months–5 years | | Subdermal | | Can be seen on
x-ray |
| | New-Fill, Sculptra | | Poly-L-lactic acid | | 24 | | Subdermal | | FDA-approved for HIV-associated lipoatrophy |
| | Alloderm | | Acellular human cadaveric dermis | | 3–6 | | Subdermal implant | | |
| | Autologous graft | | Fat harvested from patient | | 6–24 | | | | |
| | | | | | | | | | |
