Coenzyme Q10 Coenzyme Q10 (CoQ10) is a powerful free radical inhibitor that inhibits lipid peroxides from forming in plasma membranes. CoQ10 plays a very important role in cellular energy production and works in the mitochondrial adenosine triphosphate (ATP) energy-producing pathway of the cell [26]. The presence of CoQ10 in the mitochondria may play a role in preventing oxidative stress induced cellular apoptosis since it is in the mitochondria where the final apoptotic signal is dispatched. As we age, CoQ10 levels diminish, as does cellular energy production,which may improve by adding CoQ10. The vast majority of information about CoQ10 is based on its oral use. Topically, it has demonstrated antioxidant activity as well as inhibition of collagenase expression in UV-irradiated human fibroblasts. Topical application of CoQ10 has been reported to show a reduction in wrinkles; however,more studies need to be done. |
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