Superficial Thrombophlebitis

Before the advent of modern-day sclerotherapy and the use of postsclerotherapy graduated compression, both superficial and deep thrombophlebitis occurred in a significant number of sclerotherapy patients [2, 11, 12]. Superficial thrombophlebitis appears 1–4 weeks following sclerotherapy as a tender erythematous induration of the injected vein. Even when appropriate compression is used, thrombosis and perivascular inflammation may occur. Ascending phlebitis in the long saphenous vein or its tributaries can develop at the upper edge of the compression stocking. Creating a gradual transition of pressure from compressed to noncompressed vein(s) may mitigate this development. In addition to appropriate compression, drainage of thrombi after liquefaction of the clot has occurred (in approximately 2 weeks) will hasten resolution. If untreated, the inflammation and clot may spread to perforating veins and the deep venous system, leading to possible valvular damage and pulmonary embolic phenomena. Frequent ambulation and aspirin or other nonsteroidal anti-inflammatory agents may also be helpful.