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Fig. 5.5 Facial angiofibromas in tuberous sclerosis (adenoma sebaceum). |
Angiofibromas (Fig. 5-5). These lesions consist of hyperplastic blood vessels and collagen and are not tumors of sebaceous glands. Facial angiofibromas appear at 4 to 9 years of age and increase in size and number during puberty. They are firm, discrete, reddish papules of 1 to 10 mm, developing initially in the nasolabial folds and frequently progressing over the malar region, forehead, and chin.