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Fig. 19.1 Typical lesion of erythema nodosum on the leg. Erythema nodosum heals without scarring. (Courtesy of James E. Fitzpatrick, MD.) |
Erythema nodosum (Fig. 19-1) consists of an eruption of erythematous, tender nodules— typically over the pretibial areas but occasionally elsewhere—that is regarded as a hypersensitivity response to some antigenic challenge. It is typically an acute process lasting 3 to 6 weeks, but a more chronic form can occur. Some experts consider the condition termed
subacute nodular migratory panniculitis (Vilanova’s disease) to be a chronic variant of erythema nodosum.
Requena L, Yus ES: Panniculitis. Part I. Mostly septal panniculitis, J Am Acad Dermatol 45:163–683, 2001.