What is the best way to treat nevus of Ota?

Most lesions are a cosmetic issue only and treatment is not necessary unless it starts to affect the patient’s self-esteem. In the past, scarring treatment modalities such as excision and cryotherapy were utilized. In the last 10 years, the use of Q-switched ruby, alexandrite, and Nd:YAG lasers has markedly improved the cosmetic appearance of these lesions, and they have become the treatment of choice. Although malignant changes are extremely rare, nevus of Ota patients with eye involvement should be followed closely, because a majority of associated melanomas occur in the ocular region.