How many café-au-lait macules must be present on a child to make you worry about neurofibromatosis type 1 (von Recklinghausen’s disease)? Six or more café-au-lait macules >5 mm in diameter in a prepubertal child are one of the major diagnostic criteria for neurofibromatosis type 1. Lu-Emerson C, Plotkin SR: The neurofibromatoses. Part 1: NF-1, Rev Neurol Dis 6:47–53, 2009. |
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