Acute Generalized Exanthematous Pustulosis (AGEP)- Febrile drug reaction often seen within 1–2 days of starting offending drug
- Presents with punctate non-follicular sterile pustules in a background of edematous erythema; lesions appear initially on face or intertriginous areas and spread to trunk and upper extremities; ± edema of face and hands; resolves typically within 1–2 weeks with superficial desquamation
- Related drugs: β-lactam antibiotics, macrolides, calcium channel blockers (i.e., diltiazem), antimalarials, terbinafine, carbamazepine, acetaminophen
- Treatment: remove offending drug, topical corticosteroid
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