Does Hodgkin’s disease occur in the skin?

Yes, but very rarely. One series of 1800 cases reported a <5% incidence of specific skin lesions in patients with Hodgkin’s disease. Many of the early reports of Hodgkin’s disease presenting with skin lesions with no nodal involvement probably represent Ki-1–positive, T-cell lymphomas. Nonspecific skin lesions are common and include pruritus, pigmentation, prurigo, ichthyosis, alopecia, and herpes zoster.

Fernandez-Flores A: The early reports on cutaneous involvement of Hodgkin lymphoma, Am J Dermatopathol 31:853–854, 2009.