| Table 2-11 Keratinopathies |
| Type II Keratin | | Type I Keratin | | Location of Expression | | Associated Disease |
| 1 | | 10 | | Suprabasal keratinocytes | | Epidermolytic hyperkeratosis (Bullous CIE)
Unna-Thost PPK (K1)
Ichthyosis hystrix of Curth-Macklin (K1) |
| 1 | | 9 | | Palmoplantar, suprabasal
keratinocytes | | Epidermolytic PPK (Vörner) |
| 2 | | 10 | | Granular and upper spinous layer | | Ichthyosis bullosa of Siemens |
| 3 | | 12 | | Cornea | | Meesmann corneal dystrophy |
| 4 | | 13 | | Mucosal epithelium | | White sponge nevus |
| 5 | | 14 | | Basal keratinocytes | | Epidermolysis bullosa simplex (EBS)
Dowling-Degos disease (K5 alone) |
| 6 | | 16 | | Outer root sheath | | Pachyonychia congenita I (Jadassohn Lewandowsky)
Focal PPK |
| 6 | | 17 | | Nail bed | | Pachyonychia congenita II (Jackson-Lawler)
Steatocystoma multiplex |
| 8 | | 18 | | Simple epithelium | | Cryptogenic cirrhosis |
| K81 and K86 | | | | Hair | | Monilethrix |
| | | 19 | | Simple epithelium, bulge cells | | |
| 6 | | 16 | | | | Hyperproliferative keratinocytes |
| | | | | | | | |
