Cutaneous Diphtheria | Figure 4.12 A: Cutaneous diphtheria (Courtesy of Public Health Image Library: CDC) B: Cutaneous anthrax (Courtesy of James Steele, CDC) C: Erysipeloid (Reprint from Mandell G, ed. Atlas of Infectious Diseases. Philadelphia PA: Current Medicine LLC; 2002) |
(Figure 4.12A) - Localized infection of C.diphtheriae, endemic in several tropical countries, skin involvement via inoculation to an otherwise insignificant wound
- Presents as sharply bordered, punched out ulcer with yellow leathery pseudomembrane (primary disease) or preexisting wound becomes infected (secondary disease)
- If toxin produced, risk of cardiac or neurologic disease
- Treatment: dipththeria antitoxin from horse serum (before toxin binds cells) crucial, PCN or erythromycin × 10–14 days
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