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Mycobacterial Infections

»What is the classification system of mycobacteria?
»What are the staining characteristics of mycobacteria?
»How many species of Mycobacterium cause infection in human beings?
»Name three mycobacteria in the tuberculosis complex responsible for tuberculosis.
»What is tuberculosis?
»What is the difference between a primary and secondary infection?
»Explain the route of infection in cutaneous tuberculosis.
»Who is at risk of acquiring tuberculosis?
»Describe the histopathologic hallmark of tuberculosis.
»How can one acquire primary cutaneous tuberculosis?
»Describe the clinical manifestation of primary-inoculation cutaneous tuberculosis.
»What are the different types of cutaneous tuberculosis?
»What laboratory tests are used to diagnose Mycobacterium tuberculosis?
»Is lupus vulgaris related to lupus erythematosus or lupus pernio?
»Describe the clinical manifestations of lupus vulgaris.
»Where and when does lupus vulgaris develop?
»What is scrofuloderma?
»Name the vaccination against tuberculosis. What type of vaccination is it?
»What drugs are used in the treatment of tuberculosis?
»What are the major side effects of antituberculous agents?
»What factors have led to multidrug-resistant tuberculosis?
»Are there any special treatment considerations for cutaneous tuberculosis?
»What is the mechanism of action of TNF-a in tuberculosis?
»Describe the pathogenesis of the atypical mycobacteria.
»Describe the pathogenesis of the atypical mycobacteria.
»What is a “swimming pool granuloma”?
»What is a Buruli ulcer?
»Describe the clinical manifestations of Mycobacterium avium-intracellulare complex (MAC) in both non-AIDS and AIDS patients.
»Which atypical mycobacteria are associated with mesotherapy?
»Which atypical mycobacteria are associated with tattoos?
»Which atypical mycobacteria have been associated with soft tissue fillers?
»How are infections with rapidly growing mycobacteria managed?
»What are some of the key features of Mycobacterium kansasii?

 
 
 

Which atypical mycobacteria are associated with mesotherapy?

Mesotherapy is the microinjection of drugs into the dermis. It has a variety of applications and despite the dearth of scientific data, is popular in Europe and South America as a procedure to reduce fat and cellulite and to perform body contouring. It is also offered in the United States. Most often the service is delivered in nonmedical settings under nonsterile conditions. A number of cases have been reported in the literature describing infection with rapidly growing mycobacteria following mesotherapy. The organisms include M. chelonae, M. fredericksbergense, M. abscessus, and M. fortuitum.

Difonzo EM, Campanile GL, Vanzi L, Lotti L: Mesotherapy and cutaneous Mycobacterium fortuitum infection, Int J Dermatol 48(6):645– 647, 2009.

Regnier S, Cambau E, Meningaud JP, et al: Clinical management of rapidly growing mycobacterial cutaneous infections in patients after mesotherapy, Clin Infect Dis 49(9):1358–1364, 2009.