What are the skin findings in African trypanosomiasis?


A, A big game hunter returning from Africa with oval secondary lesion of African trypanosomiasis. B, Peripheral smear from the patient demonstrating a circulating trypanosome. (Courtesy of the Fitzsimons Army Medical Center teaching files.)
Fig. 33.9 A, A big game hunter returning from Africa with oval secondary lesion of African trypanosomiasis. B, Peripheral smear from the patient demonstrating a circulating trypanosome. (Courtesy of the Fitzsimons Army Medical Center teaching files.)
African trypanosomiasis, also called sleeping sickness, is due to Trypanosoma gambiense or T. rhodesiense. It may present with a trypanosomal chancre (primary cutaneous African trypanosomiasis) at the site of the bite, followed by nodules and dermatitis (secondary cutaneous African trypanosomiasis) (Fig. 33-9). The cardiac and neurologic complications of both forms of trypanosomiasis are the most serious clinical concerns.

McGovern TW, Williams W, Fitzpatrick JE, et al: Cutaneous manifestations of African trypanosomiasis, Arch Dermatol 131:1178–1182, 1995.