« Back to Special Patient Populations

Dermatoses of Pregnancy

Specific Dermatoses of Pregnancy

»Name four pregnancy-specific dermatological disorders
»What is pruritic urticarial papules and plaques of pregnancy?
»Does PUPPP have any associated morbidity?
»How is PUPPP treated?
»From which dermatosis of pregnancy must PUPPP be differentiated?
»What is pemphigoid gestationis?
»What are the antigens associated with the development on pemphigoid gestationis?
»Which histocompatibility leukocyte antigen (HLA) types have been associated with pemphigoid gestationis?
»Compare PUPPP and pemphigoid gestationis.
»What is atopic eruption of pregnancy?
»What is intrahepatic cholestasis of pregnancy?
»What is the epidemiology of ICP?
»Are there specific laboratory findings to establish the diagnosis?
»What risks and outcomes are associated with intrahepatic cholestasis of pregnancy?
»How is cholestasis of pregnancy treated?
»Is impetigo herpetiformis a distinct clinical disease?
»Are there lab findings associated with impetigo herpetiformis?
»What is the treatment for impetigo herpetiformis?

Physiologic Skin Changes in Pregnancy

»List the physiologic skin changes that can occur as a normal part of pregnancy.
»What are some of the normal pigmentary changes that can be associated with pregnancy?
»Why do these pigmentary changes occur?
»How does pregnancy affect patients with melanoma?
»Is pregnancy associated with changes in hair growth?
»List the vascular changes that can occur in pregnancy.
»What factors influence the development of striae distensae (commonly known as “stretch marks”)?
»Discuss two cutaneous tumors often associated with pregnancy.
»Do some diseases improve with pregnancy?
»Do some mucocutaneous diseases worsen in pregnancy?

 
 
 

What is pruritic urticarial papules and plaques of pregnancy?


Pruritic urticarial papules and plaques of pregnancy (PUPPP). A, Erythematous papules in the striae of a 21-year-old primigravida woman. B, Urticarial papules and plaques that are not associated with striae on the thighs of a woman with PUPPP.
Fig. 60.1 Pruritic urticarial papules and plaques of pregnancy (PUPPP). A, Erythematous papules in the striae of a 21-year-old primigravida woman. B, Urticarial papules and plaques that are not associated with striae on the thighs of a woman with PUPPP.
Pruritic urticarial papules and plaques of pregnancy (also known as polymorphic eruption of pregnancy, or PUPPP) has an incidence of 1/200 pregnancies. The onset of PUPPP is usually in the third trimester. The pruritic, erythematous, papules and plaques are usually first seen in the abdominal striae (stretch marks) and then spread to the chest, trunk, and extremities. The papules and plaques typically spare the palms, soles, face, and mucous membranes. Large vesicles or bullae are uncommon, though pinpoint vesicles may be seen (Fig. 60-1).

Ahmadi S, Powell FC: Pruritic urticarial papules and plaques of pregnancy: current status, Austr J Dermatol 46:53–60, 2005.

Matz H, Orion E, Wolf R: Pruritic urticarial papules and plaques of pregnancy: polymorphic eruption of pregnancy (PUPPP), Clin Dermatol 24(2):105–108, 2006.