Muir–Torre Syndrome- AD, mutation in MLH1 and MSH2 (DNA mismatch repair genes) causing microsatellite instability
- Multiple sebaceous neoplasms and keratoacanthomas
- ↑ Risk of colon adenocarcinoma, less common GU, lung, breast or heme malignancy
| | | | Muir –Torre: think of “more” and more sebaceous neoplasms | | | | |
|
|