Gardner Syndrome

  • AD, APC gene encoding tumor suppressor gene (ras proto-oncogene)
  • Cutaneous epidermoid cysts, osteomas (mandible, maxilla), supernumerary teeth, odontomas, fibromas, congenital hypertrophy of the retinal pigment epithelium (CHRPE)
  • Tumors: GI adenocarcinoma (inevitable), osteochondromas, thyroid papillary carcinoma, hepatoblastoma, adrenal adenomas
   
 
Gardner – birds CHiRP in the GARDen