Specific Product Contraindications Following is a list of contraindications to specific products used for soft tissue augmentation: - Bovine dermal collagen (Zyderm, Zyplast): adverse reaction to allergy test, the presence of severe allergies manifested by a history of anaphylaxis, or of multiple severe allergies. In addition, patients with known lidocaine hypersensitivity should not be injected with these fillers, nor should patients with a history of allergies to any bovine collagen product. Contraindicated for use in the glabellar region
- Injectable microparticulate acellular allogenic dermis (Cymetra): autoimmune connective-tissue disease, infected or nonvascular surgical sites unless specifically prescribed by a physician, patients sensitized to the specific antibiotics used in the manufacture of this preparation, and in periocular line correction or glabellar contouring
- Human-based collagen cross-linked with glutaraldehyde (CosmoPlast/ CosmoDerm): severe allergies manifested by a history of anaphylaxis and in patients with known lidocaine hypersensitivity. Contraindicated for use in the glabellar region, breast augmentation, and for implantation into bone, tendon, ligament, or muscle
- Viscoelastic, nonanimal hyaluronic acid (Juvederm): autoimmune diseases, pregnancy, lactation, allergies to hyaluronic acid, and direct sunlight or intense heat on the treatment area for several days postinjection.
- Hyaluronic acid (Hylaform): poultry allergy
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