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| Fig. 16.3 A, Lichen amyloidosis. Numerous pruritic, scaly papules on the anterior shin. B, Nodular amyloidosis demonstrating large waxy nodule on the nose. |
Nodular amyloidosis typically presents as solitary or multiple waxy nodules (Fig. 16-3B). Common sites of involvement include the face, scalp, lower extremities, and genitalia. It may be associated with the subsequent development of systemic amyloidosis up to 15% of cases. Rarely, it is found in association with Sjögren’s syndrome.
Kalajian AH, Waldman M, Knable AL: Nodular primary localized cutaneous amyloidosis after trauma: a case report and discussion of the rate of progression to systemic amyloidosis,
J Am Acad Dermatol 57(Suppl 2):S26–S29, 2007.
Yoneyama K, Tochigi N, Oikawa A, et al: Primary localized cutaneous nodular amyloidosis in a patient with Sjögren’s syndrome: a review of the literature,
J Dermatol 32:120–123, 2005.
