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Bullous Viral Eruptions

»What do herpes simplex (HSV) virus and varicella-zoster virus (VZV) have in common?
»What happens during primary HSV infection?
»What about recurrent infection?
»What is the difference between a primary and an initial HSV infection?
»How is HSV transmitted?
»How long is incubation period for HSV (i.e., the time from initial infection to appearance of vesicles)?
»Define asymptomatic shedding.
»Can you be infected with HSV and not know it?
»How do HSV-1 and -2 differ?
»How do you diagnose HSV infection?
»How is a Tzanck smear performed?
»What are the drugs of choice for treatment of HSV?
»When is chronic suppressive therapy indicated?
»Are patients with genital herpes at greater risk for becoming infected with the human immunodeficiency virus (HIV)?
»What recommendations can you make to a patient with genital herpes to reduce the risk of transmission to his or her partner?
»Can HSV infect the skin in areas other than around the mouth or anogenital areas?
»How does a baby get herpes? Is it a serious problem?
»Describe the natural history of varicella.
»What is shingles?
»Can herpes zoster be recurrent?
»What is disseminated zoster?
»Is herpes zoster contagious?
»What is postherpetic neuralgia?
»How do you diagnose VZV infection?
»What is the treatment for varicella?
»How about herpes zoster?
»Should I be concerned about the patient with herpes zoster involving the tip of the nose?
»Who should get the herpes zoster vaccine?
»What is hand, foot, and mouth disease?
»What is orf?

 
 
 

How does a baby get herpes? Is it a serious problem?

In most cases, transmission of HSV to the neonate occurs by delivery through an infected birth canal. Postpartum acquisition occurs less commonly. Development of primary or initial non-primary genital herpes by the mother at or near the time of delivery poses a significant risk for the infant. However, most cases of neonatal herpes are the result of asymptomatic shedding in women with no known history of genital herpes. The usual onset of neonatal herpes is 5 to 21 days following exposure. Approximately 80% of infected neonates have at least some characteristic skin lesions. Herpes infection in the neonatal period can be devastating because of the inadequate immune response seen in neonates.

Corey L, Wald A: Maternal and neonatal herpes simplex virus infections, N Engl J Med 361:1376–1385, 2009.