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| Fig. 59.3 Nodular elastosis with comedones. Numerous comedones in characteristic location associated with background of solar elastotic skin. |
Nodular elastosis with cysts and comedones, also known as Favre-Racouchot syndrome, is characterized by the presence of marked solar elastosis and comedones on the lateral and inferior periorbital areas (Fig. 59-3). Severe cases may demonstrate cysts. The reason for this regional presentation is not understood, but it has been suggested that the fibroblasts around the hair follicles are damaged by UV light and no longer produce normal elastic tissue. This predisposes to dilatation of the hair follicles, resulting in comedones and cysts. Most cases can be successfully treated with topical tretinoin cream and comedonal extraction.
Patterson WM, Fox MD, Schwartz RA: Favre-Racouchot disease,
Int J Dermatol 43:167–169, 2004.
