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Nail Disorders

»What functions do nails serve?
»Why are nails important in medicine?
»Do any systemic diseases have specific nail findings?
»What are Beau’s lines? How are they formed?
»What is a splinter hemorrhage?
»Are splinter hemorrhages always associated with subacute bacterial endocarditis?
»What is the difference between Mees’ lines and Muehrcke’s lines?
»What are “half-and-half” nails, and with what internal disease are they associated?
»What is nail fold capillaroscopy? How is it useful?
»What is clubbing?
»How is hypertrophic osteoarthropathy related to clubbing?
»What is the yellow nail syndrome?
»Are there any characteristic nail changes in primarily dermatologic diseases?
»What are nail pits?
»Are there any differences between the nail pits of psoriasis and alopecia areata?
»What other nail findings are seen in psoriasis? What is the significance of nail changes?
»How does a pterygium differ from pterygium inversus unguium?
»What is the most common cause and sequela of a subungual hematoma? How is it treated?
»Do malignant melanomas occur in the nails?
»How do you tell the difference between a subungual hematoma and a malignant melanoma?
»What nail changes are considered peculiar to human immunodeficiency virus (HIV) infection?
»What is onychocryptosis? Why does it occur?
»What is a paronychia?
»Which infectious organisms cause paronychia?
»How do you treat an acute paronychia?
»What is the most common cause of green nails?
»What is the difference between onychomycosis and tinea unguium? What organisms most commonly cause tinea unguium? Where does the infection typically start?
»List the antifungal medications most often used in the treatment of toenail onychomycosis.
»What should patients expect when undergoing treatment of onychomycosis?
»What is “habit tic” disorder? How is it different from median nail dystrophy?
»List the common benign “tumors” that occur in and around the nail unit.
»What is an exostosis?
»Name the four most common malignant tumors of the nail unit.

 
 
 

Are there any characteristic nail changes in primarily dermatologic diseases?

Unfortunately, because the nail unit has only limited ways of responding to pathologic insults, pathognomonic changes are seldom encountered. However, examination of the nails is imperative because there are certain changes that, viewed in context with the entire clinical picture, can help establish a diagnosis (Table 68-2).

Rich P: Nail disorders: diagnosis and treatment of infectious, inflammatory, and neoplastic nail conditions, Med Clin North Am 82:1171–1182, 1998.






Table 68-2. Dermatologic Disorders with Nail Changes
 DISEASEINCIDENCEFINDINGS
 
Psoriasis
 
10%–50%
 
Pits, “oil spots”
 
Alopecia areata
 
20%–50%
 
Pits
 
Lichen planus
 
10%
 
Pterygium
 
Scleroderma

Darier’s disease
 
Frequent

High
 
Pterygium inversus unguium

Wedge shaped, hyperkeratosis
 
Pityriasis rubra pilaris
 
Majority
 
Yellow-brown, hyperkeratotic