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| Fig. 13.2 Patient with foreign body reaction to cosmetic filler demonstrating erythematous papules and linear lesions at the site of bovine collagen injection. (Courtesy of the Fitzsimons Army Medical Center teaching files.) |
Yes. Numerous cosmetic fillers, including products made from collagen (Fig. 13-2), silicone, hyaluronic acid, methacrylate, and polyalkylimide, have been reported to produce foreign body granulomas. In some cases the cosmetic results have been very poor and difficult to correct. The number of reported cases is rapidly increasing as the cosmetic filler industry has rapidly expanded in the last decade and larger numbers of patients are receiving injections for cosmetic fillers.
Sanchis-Bielsa JM, Bagán JV, Poveda R, Salvador I: Foreign body granulomatous reactions to cosmetic fillers: a clinical study of 15 cases,
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 109:237–241, 2009.
Winslow CP: The management of dermal filler complications,
Facial Plast Surg 25:124–128, 2009.
