What is the typical course of granuloma annulare?

In the classic localized form of GA, the tendency is for spontaneous resolution. Recurrences are fairly common, but the recurrences tend to resolve more quickly than the original lesions. Most studies note that at 2 years postonset of GA, 50% to 80% of patients will be lesion free. However, patients who present with disseminated lesions tend to have a much more protracted course and are frequently less responsive to therapy.