What skin disease is associated with insulin-dependent diabetes, hypothyroidism, and Addison’s disease?

Vitiligo. This is a trick question. Vitiligo is not caused by deficient hormones but is an autoimmune disease that results in the destruction of melanocytes and is associated with the autoimmune endocrinopathies. Vitiligo presents clinically as white macules, most commonly on the face and hands. Vitiligo is present in 4% of patients with insulin-dependent diabetes, 7% of patients with Graves’ disease, and 15% of patients with Addison’s disease. There is also a familial predisposition to this group of diseases.