Describe measures that can be employed to diminish the pain associated with the injection of local anesthetics.- Antianxiety measures: Explain the procedure in detail to the patient, and make sure they understand what you are about to do. Premedication with oral diazepam or similar drugs may be useful for extremely anxious patients.
- Topical anesthetics: These are especially useful in children. EMLA cream (2.5% lidocaine, 2.5% prilocaine), topical lidocaine creams and gels (2% to 30%), refrigerant spray, and ice blocks may all be useful. L-M-X-4 cream (4% lidocaine) has a more rapid onset than EMLA cream and does not require a prescription.
- Increase pH of anesthetic solution: Add 8.4% sodium bicarbonate to lidocaine, in a 1:10 ratio (1 part bicarbonate, 10 parts lidocaine). Buffering an anesthetic solution in this way may shorten its duration of action. Anesthesia can be reinforced using a nonbuffered or long-acting anesthetic.
- Warm the anesthetic solution before injection.
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